HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >

Different contributions of preparatory activity in the basal ganglia and cerebellum for self-timing

This item is licensed under: Creative Commons0 1.0 Universal

Files in This Item:
elife-35676-fig1-data1-v2.zipFigure 1, source data 1: Data for Figure 1B26.2 kBzipView/Open
elife-35676-fig3-data1-v2.zipFigure 3, source data 1: Data for Figure 31.78 MBzipView/Open
elife-35676-fig3-data2-v2.zipFigure 3, source data 2: Data for Figure 3, figure supplement 1172.23 kBzipView/Open
elife-35676-fig3-data3-v2.zipFigure 3, source data 3: Data for Figure 3, figure supplement 2113.43 kBzipView/Open
elife-35676-fig3-data4-v2.zipFigure 3, source data 4: Data for Figure 3, figure supplement 3275.33 kBzipView/Open
elife-35676-fig3-figsupp1-v2.jpgFigure 3, figure supplement 1162.93 kBJPEGView/Open
elife-35676-fig3-figsupp2-v2.jpgFigure 3, figure supplement 2276.92 kBJPEGView/Open
elife-35676-fig3-figsupp3-v2.jpgFigure 3, figure supplement 3199.57 kBJPEGView/Open
elife-35676-fig4-data1-v2.zipFigure 4, source data 1: Data for Figure 42 kBzipView/Open
elife-35676-fig5-data1-v2.zipFigure 5, source data 1: Data for Figure 5241.27 kBzipView/Open
elife-35676-fig6-data1-v2.zipFigure 6, source data 1: Data for Figure 6135.44 kBzipView/Open
elife-35676-fig6-data2-v2.zipFigure 6, source data 2: Data for Figure 6, figure supplement 14.71 kBzipView/Open
elife-35676-fig6-figsupp1-v2.jpgFigure 6, figure supplement 182.97 kBJPEGView/Open
elife-35676-fig7-data1-v2.zipFigure 7, source data 1: Data for Figure 73.66 kBzipView/Open
elife-35676-transrepform-v2.docxAdditional file: Transparent reporting form246.64 kBMicrosoft Word XMLView/Open
elife-35676-v2.pdf4.08 MBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/71497

Title: Different contributions of preparatory activity in the basal ganglia and cerebellum for self-timing
Authors: Kunimatsu, Jun Browse this author →KAKEN DB
Suzuki, Tomoki W Browse this author
Ohmae, Shogo Browse this author
Tanaka, Masaki Browse this author →KAKEN DB
Issue Date: 2-Jul-2018
Publisher: eLife Sciences Publications
Journal Title: Elife
Volume: 7
Start Page: e35676
Publisher DOI: 10.7554/eLife.35676
Abstract: The ability to flexibly adjust movement timing is important for everyday life. Although the basal ganglia and cerebellum have been implicated in monitoring of supra-and sub-second intervals, respectively, the underlying neuronal mechanism remains unclear. Here, we show that in monkeys trained to generate a self-initiated saccade at instructed timing following a visual cue, neurons in the caudate nucleus kept track of passage of time throughout the delay period, while those in the cerebellar dentate nucleus were recruited only during the last part of the delay period. Conversely, neuronal correlates of trial-by-trial variation of self-timing emerged earlier in the cerebellum than the striatum. Local inactivation of respective recording sites confirmed the difference in their relative contributions to supra-and sub-second intervals. These results suggest that the basal ganglia may measure elapsed time relative to the intended interval, while the cerebellum might be responsible for the fine adjustment of self-timing.
Rights: https://creativecommons.org/publicdomain/zero/1.0/
Type: article
URI: http://hdl.handle.net/2115/71497
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 田中 真樹

Export metadata:

OAI-PMH ( junii2 , jpcoar )

MathJax is now OFF:


 

Feedback - Hokkaido University