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Nuclease Tolerant FRET Probe Based on DNA-Quantum Dot Conjugation

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Title: Nuclease Tolerant FRET Probe Based on DNA-Quantum Dot Conjugation
Authors: ONOSHIMA, Daisuke Browse this author
KAJI, Noritada Browse this author
TOKESHI, Manabu Browse this author →KAKEN DB
BABA, Yoshinobu Browse this author
Keywords: fluorescence resonance energy transfer (FRET)
Issue Date: 10-Feb-2008
Publisher: 日本分析化学会
Journal Title: Analytical Sciences
Volume: 24
Issue: 2
Start Page: 181
End Page: 183
Publisher DOI: 10.2116/analsci.24.181
Abstract: We have developed a fluorescence resonance energy transfer (FRET) probe based on the conjugation of a quantum dot (QD) with dye (YOYO-3) intercalated DNA. The FRET-inducing electrostatic coupling of DNA and the QD made structural changes to the QD-DNA conjugates, which significantly prevented an enzymatic reaction between the DNA and a conventional restriction endonuclease (EcoRI).
Type: article
Appears in Collections:工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 渡慶次 学

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