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Integration of Chemical and Biochemical Analysis Systems into a Glass Microchip.

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Title: Integration of Chemical and Biochemical Analysis Systems into a Glass Microchip.
Authors: SATO, Kiichi Browse this author
HIBARA, Akihide Browse this author
TOKESHI, Manabu Browse this author →KAKEN DB
HISAMOTO, Hideaki Browse this author
KITAMORI, Takehiko Browse this author
Keywords: glass microchips
microchip technology
Issue Date: Jan-2003
Publisher: 日本分析化学会
Journal Title: Analytical Sciences
Volume: 19
Issue: 1
Start Page: 15
End Page: 22
Publisher DOI: 10.2116/analsci.19.15
Abstract: This review focuses on the integration of chemical and biochemical analysis systems into glass microchips for general use. By combining multiphase laminar flow driven by pressure and micro unit operations, such as mixing, reaction, extraction and separation, continuous-flow chemical processing systems can be realized in the microchip format, while the application of electrophoresis-based chip technology is limited. The performances of several analysis systems were greatly improved by microchip integration because of some characteristics of microspace, i.e., a large specific interface area, a short molecular diffusion time, a small heat capacity and so on. By applying these concepts, several different analysis systems, i.e., wet analysis of cobalt ion, multi-ion sensor, immunoassay, and cellular analysis, were successfully integrated on a microchip. These microchip technologies are promising for meeting the future demands of high-throughput chemical processing.
Type: article
URI: http://hdl.handle.net/2115/71672
Appears in Collections:工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 渡慶次 学

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