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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Engineering / Faculty of Engineering >
Peer-reviewed Journal Articles, etc >
Integration of Chemical and Biochemical Analysis Systems into a Glass Microchip.
| Title: | Integration of Chemical and Biochemical Analysis Systems into a Glass Microchip. |
| Authors: | SATO, Kiichi Browse this author | | HIBARA, Akihide Browse this author | | TOKESHI, Manabu Browse this author →KAKEN DB | | HISAMOTO, Hideaki Browse this author | | KITAMORI, Takehiko Browse this author |
| Keywords: | glass microchips | | microchip technology |
| Issue Date: | Jan-2003 |
| Publisher: | 日本分析化学会 |
| Journal Title: | Analytical Sciences |
| Volume: | 19 |
| Issue: | 1 |
| Start Page: | 15 |
| End Page: | 22 |
| Publisher DOI: | 10.2116/analsci.19.15 |
| Abstract: | This review focuses on the integration of chemical and biochemical analysis systems into glass microchips for general use. By combining multiphase laminar flow driven by pressure and micro unit operations, such as mixing, reaction, extraction and separation, continuous-flow chemical processing systems can be realized in the microchip format, while the application of electrophoresis-based chip technology is limited. The performances of several analysis systems were greatly improved by microchip integration because of some characteristics of microspace, i.e., a large specific interface area, a short molecular diffusion time, a small heat capacity and so on. By applying these concepts, several different analysis systems, i.e., wet analysis of cobalt ion, multi-ion sensor, immunoassay, and cellular analysis, were successfully integrated on a microchip. These microchip technologies are promising for meeting the future demands of high-throughput chemical processing. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/71672 |
| Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 渡慶次 学
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