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Integration of Flow Injection Analysis and Zeptomole-Level Detection of the Fe(II)-<i>o</i>-Phenanthroline Complex
Title: | Integration of Flow Injection Analysis and Zeptomole-Level Detection of the Fe(II)-<i>o</i>-Phenanthroline Complex |
Authors: | SATO, Kiyoshi Browse this author | TOKESHI, Manabu Browse this author →KAKEN DB | KITAMORI, Takehiko Browse this author | SAWADA, Tsuguo Browse this author |
Keywords: | On-chip integration | flow injection analysis | photochemical microscope | molecular diffusion |
Issue Date: | Jul-1999 |
Publisher: | 日本分析化学会 |
Journal Title: | Analytical Sciences |
Volume: | 15 |
Issue: | 7 |
Start Page: | 641 |
End Page: | 645 |
Publisher DOI: | 10.2116/analsci.15.641 |
Abstract: | Microchannels having a 150×100 µm cross section were fabricated in a quartz glass chip as a component in an integrated flow injection analysis (FIA) system. They were put to use for flow, mixing, reaction, and detection. The reaction system was a chelating reaction of divalent iron ion with o-phenanthroline (o-phen), and a photothermal microscope was applied for the ultra-sensitive detection of the non-fluorescent reaction product. Nano liter levels of solutions were introduced and transported by capillary action and mixed by molecular diffusion. Zeptomole levels of the reaction product were detected quantitatively. This was the first demonstration of an on-chip chemical determination device which integrates the primitive FIA system without using electroosmotic liquid control or fluorometric determination. |
Type: | article |
URI: | http://hdl.handle.net/2115/71677 |
Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 渡慶次 学
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