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Ergothioneine production with Aspergillus oryzae

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Title: Ergothioneine production with Aspergillus oryzae
Authors: Takusagawa, Shun Browse this author
Satoh, Yasuharu Browse this author →KAKEN DB
Ohtsu, Iwao Browse this author
Dairi, Tohru Browse this author →KAKEN DB
Keywords: Ergothioneine
molecular breeding
heterologous expression
Aspergillus oryzae
Neurospora crassa
Issue Date: Jan-2019
Publisher: Taylor & Francis
Journal Title: Bioscience biotechnology and biochemistry
Volume: 83
Issue: 1
Start Page: 181
End Page: 184
Publisher DOI: 10.1080/09168451.2018.1527210
Abstract: To establish a reliable and practical ergothioneine (ERG) supply, we employed fermentative ERG production using Aspergillus oryzae, a fungus used for food production. We heterologously overexpressed the egt-1 and -2 genes of Neurospora crassa in A. oryzae and succeeded in producing ERG (231.0 mg/kg of media, which was 20 times higher than the wild type).
Rights: This is an Accepted Manuscript of an article published by Taylor & Francis in Bioscience, biotechnology, and biochemistry on Jan. 2019, available online:
Type: article (author version)
Appears in Collections:工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 佐藤 康治

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