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Ergothioneine production with Aspergillus oryzae
Title: | Ergothioneine production with Aspergillus oryzae |
Authors: | Takusagawa, Shun Browse this author | Satoh, Yasuharu Browse this author →KAKEN DB | Ohtsu, Iwao Browse this author | Dairi, Tohru Browse this author →KAKEN DB |
Keywords: | Ergothioneine | molecular breeding | heterologous expression | Aspergillus oryzae | Neurospora crassa |
Issue Date: | Jan-2019 |
Publisher: | Taylor & Francis |
Journal Title: | Bioscience biotechnology and biochemistry |
Volume: | 83 |
Issue: | 1 |
Start Page: | 181 |
End Page: | 184 |
Publisher DOI: | 10.1080/09168451.2018.1527210 |
Abstract: | To establish a reliable and practical ergothioneine (ERG) supply, we employed fermentative ERG production using Aspergillus oryzae, a fungus used for food production. We heterologously overexpressed the egt-1 and -2 genes of Neurospora crassa in A. oryzae and succeeded in producing ERG (231.0 mg/kg of media, which was 20 times higher than the wild type). |
Rights: | This is an Accepted Manuscript of an article published by Taylor & Francis in Bioscience, biotechnology, and biochemistry on Jan. 2019, available online: http://www.tandfonline.com/10.1080/09168451.2018.1527210. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/76446 |
Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 佐藤 康治
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