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A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates
| Title: | A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates |
| Authors: | Ikeuchi, Kazutada Browse this author | | Murasawa, Kentaro Browse this author | | Yamada, Hidetoshi Browse this author |
| Keywords: | preparation | | 2 | | 2 | | 2-trichloroacetimidates | | stainless | | solvent optimization | | visual detection |
| Issue Date: | Jul-2019 |
| Publisher: | Georg Thieme Verlag |
| Journal Title: | Synlett |
| Volume: | 30 |
| Issue: | 11 |
| Start Page: | 1308 |
| End Page: | 1312 |
| Publisher DOI: | 10.1055/s-0037-1611551 |
| Abstract: | We describe a method for obtaining various allylic, benzylic, and glucosyl 2,2,2-trichloroacetimidates (TCAIs) as stainless liquids or solids at the crude stage. The general synthetic method for the preparation of TCAIs often leads to stained products, and further purification of crude TCAIs causes decomposition due to their instability. In the described method, we use a solvent that barely dissolves the reactant, providing stainless and sufficiently pure TCAIs without requiring a purification step. Furthermore, the reaction mixture is turbid at the beginning and clear at the end, allowing us to monitor the progress of the reaction visually. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/78010 |
| Appears in Collections: | 理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 池内 和忠
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