Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Engineering / Faculty of Engineering >
Peer-reviewed Journal Articles, etc >
Concise Synthesis of Potassium Acyltrifluoroborates from Aldehydes through Copper(I)-Catalyzed Borylation/Oxidation
Title: | Concise Synthesis of Potassium Acyltrifluoroborates from Aldehydes through Copper(I)-Catalyzed Borylation/Oxidation |
Authors: | Taguchi, Jumpei Browse this author | Takeuchi, Takumi Browse this author | Takahashi, Rina Browse this author | Masero, Fabio Browse this author | Ito, Hajime Browse this author →KAKEN DB |
Keywords: | acylboron compounds | amino acids | boron | copper | oxidation |
Issue Date: | 27-May-2019 |
Publisher: | Wiley-Blackwell |
Journal Title: | Angewandte chemie-international edition |
Volume: | 58 |
Issue: | 22 |
Start Page: | 7299 |
End Page: | 7303 |
Publisher DOI: | 10.1002/anie.201901748 |
Abstract: | Potassium acyltrifluoroborates (KATs) were prepared through copper(I)-catalyzed borylation of aldehydes and subsequent oxidation. This synthetic route is characterized by the wide range of aldehydes accessible, favorable step economy, mild reaction conditions, and tolerance of various functional groups, and it enables the facile generation of a range of KATs, for example, bearing halide, sulfide, acetal, or ester moieties. Moreover, this method was applied to the three-step synthesis of various alpha -amino acid analogues that bear a KAT moiety on the C-terminus by using naturally occurring amino acids as the starting material. |
Rights: | This is the peer reviewed version of the following article: J. Taguchi, T. Takeuchi, R. Takahashi, F. Masero, H. Ito, Angew. Chem. Int. Ed. 2019, 58, 7299. , which has been published in final form at https://doi.org/10.1002/anie.201901748. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/78214 |
Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 伊藤 肇
|