The production of Sn-117m by charged-particle induced reactions is an interesting topic for medical application. Production cross sections of alpha-induced reactions on In-nat for Sn-117m up to 50 MeV were measured using the stacked foil technique and activation method. The integral yield of Sn-117m was estimated using the measured cross sections. The results were compared with experimental data investigated earlier and theoretical calculation. Measured cross sections for Sn-113 and Sb-116m,Sb-117,Sb-118m isotopes were also presented.