Effect of microtubule immobilization by glutaraldehyde on kinesin-driven cargo transport


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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/79024

Title:	Effect of microtubule immobilization by glutaraldehyde on kinesin-driven cargo transport
Authors:	Nasrin, Syeda Rubaiya Browse this author
	Kabir, Arif Md. Rashedul Browse this author
	Sada, Kazuki Browse this author
	Kakugo, Akira Browse this author →KAKEN DB
Issue Date:	4-Feb-2020
Publisher:	Nature Publishing Group
Journal Title:	Polymer journal
Volume:	52
Start Page:	655
End Page:	660
Publisher DOI:	10.1038/s41428-020-0309-x
Abstract:	The glutaraldehyde fixation method for fixing tissues is attractive for its ease of use and straightforward surface chemistry. We investigated the effect of glutaraldehyde-induced microtubule immobilization on kinesin-driven cargo transport along microtubules and found that at low glutaraldehyde concentrations, the microtubule-kinesin interaction remains unperturbed. Such findings may facilitate the application of the glutaraldehyde fixation method for many in vitro studies aiming to build nanodevices powered by the microtubule-motor protein interaction.
Type:	article (author version)
URI:	http://hdl.handle.net/2115/79024
Appears in Collections:	理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 角五彰

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