Hokkaido University Collection of Scholarly and Academic Papers >
Faculty of Pharmaceutical Sciences >
Peer-reviewed Journal Articles, etc >
Catalytic Enantioselective Methylene C(sp(3))-H Amidation of 8-Alkylquinolines Using a Cp*Rh-III/Chiral Carboxylic Acid System
Title: | Catalytic Enantioselective Methylene C(sp(3))-H Amidation of 8-Alkylquinolines Using a Cp*Rh-III/Chiral Carboxylic Acid System |
Authors: | Fukagawa, Seiya Browse this author | Kojima, Masahiro Browse this author | Yoshino, Tatsuhiko Browse this author →KAKEN DB | Matsunaga, Shigeki Browse this author →KAKEN DB |
Keywords: | asymmetric catalysis | C-H activation | chiral carboxylic acid | quinoline | rhodium |
Issue Date: | 8-Oct-2019 |
Publisher: | Wiley-Blackwell |
Journal Title: | Angewandte chemie-international edition |
Volume: | 58 |
Issue: | 50 |
Start Page: | 18154 |
End Page: | 18158 |
Publisher DOI: | 10.1002/anie.201911268 |
Abstract: | Catalytic enantioselective directed methylene C(sp(3))-H amidation reactions of 8-alkylquinolines using a Cp*Rh-III/chiral carboxylic acid (CCA) hybrid catalytic system are described. A binaphthyl-based chiral carboxylic acid efficiently differentiates between the enantiotopic methylene C-H bonds, which leads to the formation of C-N bonds with good enantioselectivity. |
Rights: | This is the peer reviewed version of the following article: Seiya Fukagawa et al. Catalytic Enantioselective Methylene C(sp3)−H Amidation of 8‐Alkylquinolines Using a Cp*RhIII/Chiral Carboxylic Acid System. Angewandte chemie-international edition, 2019, 58(50), 18154-18158, which has been published in final form at https://doi.org/10.1002/anie.201911268. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/79493 |
Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 吉野 達彦
|