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Simulation study for cross-sectional absorption distribution in turbid medium using spatially resolved backscattered light with lateral scanning and one-dimensional solution of nonlinear inverse problem

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Title: Simulation study for cross-sectional absorption distribution in turbid medium using spatially resolved backscattered light with lateral scanning and one-dimensional solution of nonlinear inverse problem
Authors: Nishida, Kazuhiro Browse this author
Kato, Yuji Browse this author →KAKEN DB
Kudo, Nobuki Browse this author →KAKEN DB
Shimizu, Koichi Browse this author →KAKEN DB
Keywords: Biomedical application
Cross-sectional imaging
Optical computed tomography
Nonlinear inverse problem
Backscattered light
Issue Date: 1-Jul-2021
Publisher: IOP Publishing
Journal Title: Japanese Journal of Applied Physics (JJAP)
Volume: 60
Issue: 7
Start Page: 072008
Publisher DOI: 10.35848/1347-4065/ac0cba
Abstract: For a practical technique of cross-sectional imaging of animal bodies, we developed a new method using spatially resolved backscattered light. This method is based on the solution of the one-dimensional nonlinear inverse problem, and on the lateral scan of the source-detector pair along the object surface. Using this method, unknown variables in inverse problems can be reduced more greatly than when using conventional methods. A stable solution for the inverse problem becomes possible. The possibility of using the proposed method was assessed using simulation analysis. The results verified that cross-sectional imaging from several to 10 millimeter depths is possible for animal tissue. This analysis clarified the specific spatial resolution and accuracy in the estimated absorption coefficient. Distortionless imaging was confirmed. Results suggest that the proposed method represents new options as a stable and practical method for biological cross-sectional imaging.
Rights: This article is published under a CC BY licence. The Version of Record is available online at 10.35848/1347-4065/ac0cba.
Type: article
URI: http://hdl.handle.net/2115/82408
Appears in Collections:情報科学院・情報科学研究院 (Graduate School of Information Science and Technology / Faculty of Information Science and Technology) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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