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Transition-metal-free Nucleophilic 211At-astatination of Spirocyclic Aryliodonium Ylides

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Title: Transition-metal-free Nucleophilic 211At-astatination of Spirocyclic Aryliodonium Ylides
Authors: Matsuoka, Keitaro Browse this author
Obata, Honoka Browse this author
Nagatsu, Kotaro Browse this author
Kojima, Masahiro Browse this author →KAKEN DB
Yoshino, Tatsuhiko Browse this author →KAKEN DB
Ogawa, Mikako Browse this author →KAKEN DB
Matsunaga, Shigeki Browse this author →KAKEN DB
Issue Date: 4-Jan-2021
Publisher: Royal Society of Chemistry
Journal Title: Organic & biomolecular chemistry
Volume: 19
Start Page: 5525
End Page: 5528
Publisher DOI: 10.1039/d1ob00789k
Abstract: The transition-metal-free At-211-astatination of spirocyclic aryliodonium ylides via a nucleophilic aromatic substitution reaction is described. This method enables the preparation of At-211-radiolabeled compounds derived from multi-functionalized molecules and heteroarenes in good to excellent radiochemical yields.
Type: article (author version)
Appears in Collections:薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 吉野 達彦

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