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Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study
| Title: | Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study |
| Authors: | Hirayama, Emi Browse this author | | Ebina, Yasuhiko Browse this author →KAKEN DB | | Kato, Kei Browse this author | | Akabane-Nakagawa, Kinuko Browse this author | | Okuyama, Kazuhiko Browse this author |
| Keywords: | cervical insufficiency | | cervical polyp | | late abortion | | retrospective cohort study | | risk factors | | spontaneous preterm birth |
| Issue Date: | 20-Jan-2021 |
| Publisher: | John Wiley & Sons |
| Journal Title: | International Journal Of Gynecology & Obstetrics |
| Volume: | 156 |
| Issue: | 1 |
| Start Page: | 64 |
| End Page: | 70 |
| Publisher DOI: | 10.1002/ijgo.13608 |
| PMID: | 33471369 |
| Abstract: | Objective To determine the association between cervical polyps in early pregnancy and late abortion and spontaneous preterm birth (SPTB). We also aimed to explore the relationship between cervical polyps and cervical insufficiency in the second trimester. Methods We conducted a retrospective cohort study of 2941 singleton pregnant women between January 2010 and December 2015. The frequency of late abortion and SPTB (before 28, 34, or 37 weeks of pregnancy) was compared between the two groups of 142 (4.8%) patients who had cervical polyps early in the pregnancy (P group) and 2799 who did not (non-P group). Multivariate analysis was performed to identify risk factors for late abortion and SPTB. Results The incidence of late abortion and SPTB was significantly higher in the P group than in the non-P group. Cervical polyps in early pregnancy were selected as independent risk factors for late abortion and SPTB before 28, 34, or 37 weeks of pregnancy. The P group had a significantly higher rate of cases requiring therapeutic cervical cerclage than the non-P group. Conclusion Cervical polyps in early pregnancy are risk factors for late abortion and SPTB. They are also associated with the occurrence of cervical insufficiency. |
| Rights: | This is the peer reviewed version of the following article: Hirayama, E., Ebina, Y., Kato, K., Akabane‐Nakagawa, K. and Okuyama, K. (2021), Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study. Int J Gynecol Obstet, 156(1): 64-70, which has been published in final form at https://doi.org/10.1002/ijgo.13608. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/83845 |
| Appears in Collections: | 保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 蝦名 康彦
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