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Autograft of Demineralized Dentin Matrix Prepared Immediately after Extraction for Horizontal Bone Augmentation of the Anterior Atrophic Maxilla: A First Case of Non-Vital Tooth-Derived Dentin
| Title: | Autograft of Demineralized Dentin Matrix Prepared Immediately after Extraction for Horizontal Bone Augmentation of the Anterior Atrophic Maxilla: A First Case of Non-Vital Tooth-Derived Dentin |
| Authors: | Okubo, Naoto Browse this author →KAKEN DB | | Ishikawa, Masahiro Browse this author | | Shakya, Mamata Browse this author | | Hosono, Hidetaka Browse this author | | Maehara, Osamu Browse this author →KAKEN DB | | Ohkawara, Tatsuya Browse this author →KAKEN DB | | Ohnishi, Shunsuke Browse this author →KAKEN DB | | Akazawa, Toshiyuki Browse this author →KAKEN DB | | Murata, Masaru Browse this author →KAKEN DB |
| Keywords: | Dentin | | DDM | | Autograft | | Bone augmentation | | Atrophic maxilla |
| Issue Date: | 31-Jan-2022 |
| Publisher: | The Society for Hard Tissue Regenerative Biology |
| Journal Title: | Journal of hard tissue biology |
| Volume: | 31 |
| Issue: | 1 |
| Start Page: | 47 |
| End Page: | 54 |
| Publisher DOI: | 10.2485/jhtb.31.47 |
| Abstract: | Onlay bone augmentation is a challenging field, especially in esthetic zones. In implant dentistry, labial bone loss is generally recovered through autologous bone and/or biomaterials. Dental pioneers have been applying a patient-own demineralized dentin matrix (DDM) for bone regeneration. The aim of this study was to histologically and radiologically evaluate horizontal bone augmentation on an anterior atrophic maxilla using an autograft of non-vital tooth-derived DDM for implant. A 56-year-old female patient presented with severe labial bone loss. Autologous DDM was immediately prepared for horizontal ridge augmentation. DDM blocks were fixed with titanium screws for lateral augmentation. DDM granules were grafted on the atrophic bone between the DDM blocks. Twelve months postoperatively, bone biopsy was performed from the implant placement point for histological observation. X-ray computed tomography (CT) was performed before and after the DDM graft surgery. Hematoxylin and eosin sections showed that new bones were directly generated on the DDM residue. CT images showed the original buccal bone lines and root-type and wall-type DDM. The grafted DDMs were clearly found on the original bone. The outlines in the 22nd region indicated an 8.11 mm horizontal width after the implant placements compared to 4.95 mm before the augmentation. Additionally, the width at the upper level increased from 3.38 mm to 5.92 mm. DDM scaffolds contributed to the horizontal bony support required to place the implants. The patient experienced therapeutic success with DDM immediate autograft and implant surgery. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/85200 |
| Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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