| Title: | Predictors of the need for prophylactic percutaneous endoscopic gastrostomy in head and neck cancer patients treated with concurrent chemoradiotherapy |
| Authors: | Kano, Satoshi Browse this author →KAKEN DB |
| Tsushima, Nayuta Browse this author |
| Suzuki, Takayoshi Browse this author |
| Hamada, Seijiro Browse this author |
| Yokokawa, Taizo Browse this author |
| Idogawa, Hiroshi Browse this author |
| Yasuda, Koichi Browse this author |
| Minatogawa, Hideki Browse this author |
| Dekura, Yasuhiro Browse this author |
| Aoyama, Hidefumi Browse this author |
| Homma, Akihiro Browse this author →KAKEN DB |
| Keywords: | PEG |
| Head and neck cancer |
| Chemoradiotherapy |
| Issue Date: | Jul-2021 |
| Publisher: | Springer |
| Journal Title: | International journal of clinical oncology |
| Volume: | 26 |
| Issue: | 7 |
| Start Page: | 1179 |
| End Page: | 1187 |
| Publisher DOI: | 10.1007/s10147-021-01889-w |
| Abstract: | Background We investigated whether prophylactic percutaneous endoscopic gastrostomy (PEG) is used effectively for patients treated with definitive concurrent chemoradiotherapy (CCRT) and the predictors of the need for PEG. Methods 326 patients with laryngeal, oropharyngeal or hypopharyngeal cancers were retrospectively reviewed. Results The PEG tube use group had more favorable results than the total parenteral nutrition and nasogastric tube groups in terms of rate of serum albumin loss, incidence of severe fever and aspiration pneumonia, CCRT completion rate and hospitalization period. However, it was inferior to oral intake. Analysis of the relative risk of requiring enteral or parenteral nutrition revealed that performance status (PS) 2, primary site (supraglottis, oropharynx, or hypopharynx), N3 disease, and cisplatin were predictors of the need for nutritional support. Conclusions Prophylactic PEG is effective for patients treated with definitive CCRT and is especially required for patients with PS2 or oropharyngeal cancer. |
| Rights: | This is a post-peer-review, pre-copyedit version of an article published in International Journal of Clinical Oncology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s10147-021-01889-w |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/85700 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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