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Hokkaido University Collection of Scholarly and Academic Papers >
Faculty of Pharmaceutical Sciences >
Peer-reviewed Journal Articles, etc >
Cp*Rh(III)/Boron Hybrid Catalysis for Directed C–H Addition to β-
Substituted α,β-Unsaturated Carboxylic Acids
| Title: | Cp*Rh(III)/Boron Hybrid Catalysis for Directed C–H Addition to β-
Substituted α,β-Unsaturated Carboxylic Acids |
| Authors: | Tanaka, Ryo Browse this author | | Hirata, Yuki Browse this author | | Kojima, Masahiro Browse this author →KAKEN DB | | Yoshino, Tatsuhiko Browse this author →KAKEN DB | | Matsunaga, Shigeki Browse this author →KAKEN DB |
| Issue Date: | 29-Nov-2021 |
| Publisher: | Royal Society of Chemistry |
| Journal Title: | Chemical communications |
| Volume: | 58 |
| Start Page: | 76 |
| End Page: | 79 |
| Publisher DOI: | 10.1039/d1cc05956d |
| Abstract: | The C-H bond addition reaction of 2-phenylpyridine derivatives with alpha,beta-unsaturated carboxylic acids catalyzed by Cp*Rh(iii)/BH3 center dot SMe2 is reported. Activation of C-H bonds with the rhodium catalyst and activation of alpha,beta-unsaturated carboxylic acids with the boron catalyst cooperatively work, and a BINOL-urea hybrid ligand significantly improved the reactivity. With the optimized hybrid catalytic system, various beta-disubstituted carboxylic acids were obtained under mild reaction conditions. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/87679 |
| Appears in Collections: | 薬学研究院 (Faculty of Pharmaceutical Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 吉野 達彦
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