Type | Author(s) | Title | Other Titles | Citation | Citation(alt) | Issue Date |
article | Kawamura, Eriko; Maruyama, Minako; Abe, Jiro; Sudo, Akira; Takeda, Atsuhito; Takada, Shingo; Yokota, Takashi; Kinugawa, Shintaro; Harashima, Hideyoshi; Yamada, Yuma | Validation of Gene Therapy for Mutant Mitochondria by Delivering Mitochondrial RNA Using a MITO-Porter | - | Molecular therapy. Nucleic acids | - | 5-Jun-2020 |
article | Yamada, Yuma; Somiya, Kana; Miyauchi, Akihiko; Osaka, Hitoshi; Harashima, Hideyoshi | Validation of a mitochondrial RNA therapeutic strategy using fibroblasts from a Leigh syndrome patient with a mutation in the mitochondrial ND3 gene | - | Scientific reports | - | 5-May-2020 |
article | Sato, Yusuke; Okabe, Nana; Note, Yusuke; Hashiba, Kazuki; Maeki, Masatoshi; Tokeshi, Manabu; Harashima, Hideyoshi | Hydrophobic scaffolds of pH-sensitive cationic lipids contribute to miscibility with phospholipids and improve the efficiency of delivering short interfering RNA by small-sized lipid nanoparticles | - | Acta biomaterialia | - | 15-Jan-2020 |
article (author version) | Kimura, Seigo; Khalil, Ikramy A.; Elewa, Yaser H. A.; Harashima, Hideyoshi | Spleen selective enhancement of transfection activities of plasmid DNA driven by octaarginine and an ionizable lipid and its implications for cancer immunization | - | Journal of controlled release | - | 10-Nov-2019 |
article (author version) | Sakurai, Yu; Kato, Akari; Hida, Yasuhiro; Hamada, Junichi; Maishi, Nako; Hida, Kyoko; Harashima, Hideyoshi | Synergistic Enhancement of Cellular Uptake With CD44-Expressing Malignant Pleural Mesothelioma by Combining Cationic Liposome and Hyaluronic Acid-Lipid Conjugate | - | Journal of Pharmaceutical Sciences | - | Oct-2019 |
article | Endo, Rikito; Nakamura, Takashi; Kawakami, Kyoko; Sato, Yusuke; Harashima, Hideyoshi | The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy | - | Scientific reports | - | 5-Aug-2019 |
article | Sakurai, Yu; Hada, Tomoya; Kato, Akari; Hagino, Yuta; Mizumura, Wataru; Harashima, Hideyoshi | Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis | - | Molecular therapy oncolytics | - | 21-Dec-2018 |
article (author version) | Abbasi, Saed; Kajimoto, Kazuaki; Harashima, Hideyoshi | Critical parameters dictating efficiency of membrane-mediated drug transfer using nanoparticles | - | International journal of pharmaceutics | - | 20-Dec-2018 |
article (author version) | Sato, Yusuke; Matsui, Hideki; Sato, Risa; Harashima, Hideyoshi | Neutralization of negative charges of siRNA results in improved safety and efficient gene silencing activity of lipid nanoparticles loaded with high levels of siRNA | - | Journal of controlled release | - | 28-Aug-2018 |
article (author version) | Khalil, Ikramy A.; Kimura, Seigo; Sato, Yusuke; Harashima, Hideyoshi | Synergism between a cell penetrating peptide and a pH-sensitive cationic lipid in efficient gene delivery based on double-coated nanoparticles | - | Journal of controlled release | - | 10-Apr-2018 |
article (author version) | Ishikawa, Takuya; Somiya, Kana; Munechika, Reina; Harashima, Hideyoshi; Yamada, Yuma | Mitochondrial transgene expression via an artificial mitochondrial DNA vector in cells from a patient with a mitochondrial disease | - | Journal of controlled release | - | 28-Mar-2018 |
article (author version) | Khalil, Ikramy A.; Harashima, Hideyoshi | An efficient PEGylated gene delivery system with improved targeting : Synergism between octaarginine and a fusogenic peptide | - | International journal of pharmaceutics | - | 1-Mar-2018 |
article (author version) | Yamada, Yuma; Tabata, Mai; Abe, Jiro; Nomura, Masatoshi; Harashima, Hideyoshi | In Vivo Transgene Expression in the Pancreas by the Intraductal Injection of Naked Plasmid DNA | - | Journal of Pharmaceutical Sciences | - | Feb-2018 |
article (author version) | Yamamoto, Shoshiro; Sakurai, Yu; Harashima, Hideyoshi | Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption | - | International journal of pharmaceutics | - | 30-Jan-2018 |
article (author version) | Kajimoto, Kazuaki; Katsumi, Tatsuhito; Nakamura, Takashi; Kataoka, Masatoshi; Harashima, Hideyoshi | Liposome Microencapsulation for the Surface Modification and Improved Entrapment of Cytochrome c for Targeted Delivery | - | Journal of the American Oil Chemists' Society | - | Jan-2018 |
article | Yamada, Yuma; Burger, Laila; Kawamura, Eriko; Harashima, Hideyoshi | Packaging of the Coenzyme Q(10) into a Liposome for Mitochondrial Delivery and the Intracellular Observation in Patient Derived Mitochondrial Disease Cells | - | Biological & pharmaceutical bulletin | - | Dec-2017 |
article (author version) | Miura, Naoya; Tange, Kota; Nakai, Yuta; Yoshioka, Hiroki; Harashima, Hideyoshi; Akita, Hidetaka | Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation | - | Journal of Pharmaceutical Sciences | - | Oct-2017 |
article (author version) | Hashiba, Kazuki; Sato, Yusuke; Harashima, Hideyoshi | pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes | - | Journal of controlled release | - | 28-Sep-2017 |
article (author version) | Yamada, Yuma; Ishikawa, Takuya; Harashima, Hideyoshi | Validation of the use of an artificial mitochondrial reporter DNA vector containing a Cytomegalovirus promoter for mitochondrial transgene expression | - | Biomaterials | - | Aug-2017 |
article (author version) | Kamiya, Hiroyuki; Nishigaki, Natsuki; Ikeda, Akihiro; Yukawa, Seiya; Morita, Yukiko; Nakatsu, Yoshimichi; Tsuzuki, Teruhisa; Harashima, Hideyoshi | Insertion and Deletion Mismatches Distant from the Target Position Improve Gene Correction with a Tailed Duplex | - | Nucleosides, nucleotides & nucleic acids | - | 3-Jul-2017 |