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Microtubule bundle formation driven by ATP : the effect of concentrations of kinesin, streptavidin and microtubules

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Title: Microtubule bundle formation driven by ATP : the effect of concentrations of kinesin, streptavidin and microtubules
Authors: Kawamura, Ryuzo Browse this author
Kakugo, Akira Browse this author →KAKEN DB
Osada, Yoshihito Browse this author →KAKEN DB
Gong, Jian Ping Browse this author →KAKEN DB
Issue Date: 9-Apr-2010
Publisher: IOP Publishing
Journal Title: Nanotechnology
Volume: 21
Issue: 14
Start Page: 145603
Publisher DOI: 10.1088/0957-4484/21/14/145603
PMID: 20215659
Abstract: Recently, a method was established for the formation of microtubule (MT) assemblies by an active self-organization (AcSO) process, in which MTs were crosslinked during sliding motion on a kinesin-coated surface, and this was coupled with adenosine triphosphate (ATP) hydrolysis. Streptavidin (ST) was the glue used to crosslink biotin-labeled MTs. Although most of the MT assemblies were in the bundle form, they varied in size, shape and motility, depending on the initial conditions used. In this paper, we systematically examined the effects of the concentrations of kinesin, ST and MT on the formation of MT bundles under the initial conditions of the process.
Rights: This is an author-created, un-copyedited version of an article accepted for publication in Nanotechnology. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at 10.1088/0957-4484/21/14/145603
Type: article (author version)
Appears in Collections:理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 龔 剣萍 (Gong Jian Ping)

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