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Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment

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Title: Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment
Authors: Yasui, Takao Browse this author
Morikawa, Jumpei Browse this author
Kaji, Noritada Browse this author →KAKEN DB
Tokeshi, Manabu Browse this author →KAKEN DB
Tsubota, Kazuo Browse this author
Baba, Yoshinobu Browse this author →KAKEN DB
Keywords: dry eye
autologous serum eye-drops
spiral microchannel
Issue Date: 4-Jul-2016
Publisher: MDPI
Journal Title: Micromachines
Volume: 7
Issue: 7
Start Page: 113
Publisher DOI: 10.3390/mi7070113
Abstract: Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide benefits for all dry eye patients; 100% and 90% removal efficiencies are achieved for 10 μm microbeads and whole human blood cells, respectively. Since our strategy allows researchers to integrate other functional microchannels into one device, such a microfluidic device will be able to offer a new one-step preparation system for autologous serum eye-drops.
Rights: https://creativecommons.org/licenses/by/4.0/
Type: article
URI: http://hdl.handle.net/2115/63211
Appears in Collections:工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 渡慶次 学

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