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Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment
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Title: | Microfluidic Autologous Serum Eye-Drops Preparation as a Potential Dry Eye Treatment |
Authors: | Yasui, Takao Browse this author | Morikawa, Jumpei Browse this author | Kaji, Noritada Browse this author →KAKEN DB | Tokeshi, Manabu Browse this author →KAKEN DB | Tsubota, Kazuo Browse this author | Baba, Yoshinobu Browse this author →KAKEN DB |
Keywords: | dry eye | autologous serum eye-drops | spiral microchannel |
Issue Date: | 4-Jul-2016 |
Publisher: | MDPI |
Journal Title: | Micromachines |
Volume: | 7 |
Issue: | 7 |
Start Page: | 113 |
Publisher DOI: | 10.3390/mi7070113 |
Abstract: | Dry eye is a problem in tearing quality and/or quantity and it afflicts millions of persons worldwide. An autologous serum eye-drop is a good candidate for dry eye treatment; however, the eye-drop preparation procedures take a long time and are relatively troublesome. Here we use spiral microchannels to demonstrate a strategy for the preparation of autologous serum eye-drops, which provide benefits for all dry eye patients; 100% and 90% removal efficiencies are achieved for 10 μm microbeads and whole human blood cells, respectively. Since our strategy allows researchers to integrate other functional microchannels into one device, such a microfluidic device will be able to offer a new one-step preparation system for autologous serum eye-drops. |
Rights: | https://creativecommons.org/licenses/by/4.0/ |
Type: | article |
URI: | http://hdl.handle.net/2115/63211 |
Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 渡慶次 学
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