Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae


Hokkaido University \| Library \| HUSCAP	Advanced Search		言語

	Home
	About HUSCAP
	Open Access Policy

	Browse by Author

Browse
	Communities & Collections

	Scholarly Journals
	Theses
	Doctoral Dissertations Listed by Graduate Schools
	Conference Procs.
	Events

	HUSCAP Senior (in Japanese)

	Societies

	Downloads (country)

For university staff
	How to post your papers to HUSCAP
	Publication of theses
	Helpline about theses publication

Open Archives Compliant

You can search our collection also at:
	Google
	Google Scholar
	CiNii
	IRDB
	OAIster
	NDLTD

Files in This Item:

Dojun-Dalton.pdf

837.31 kB

PDF

Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/70026

Title:	Iron chelators inhibit the heme-degradation reaction by HutZ from Vibrio cholerae
Authors:	Dojun, Nobuhiko Browse this author
	Sekine, Yukari Browse this author
	Ishimori, Koichiro Browse this author →KAKEN DB
	Uchida, Takeshi Browse this author →KAKEN DB
Issue Date:	28-Apr-2017
Publisher:	Royal Society of Chemistry
Journal Title:	Dalton transactions
Volume:	46
Issue:	16
Start Page:	5147
End Page:	5150
Publisher DOI:	10.1039/c7dt00121e
PMID:	28352909
Abstract:	HutZ is a heme-degrading enzyme. We found that the heme-degradation reaction by HutZ is inhibited by the iron chelators. Kinetic analysis of each heme-degradation step suggests that water molecules hydrogen bonded to Thr27 are involved in proton transfer to Fe(III)-OO-, and that this step is inhibited by iron chelators.
Type:	article (author version)
URI:	http://hdl.handle.net/2115/70026
Appears in Collections:	理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 内田毅

OAI-PMH ( junii2 , jpcoar_1.0 )

- Hokkaido University