|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Engineering / Faculty of Engineering >
Peer-reviewed Journal Articles, etc >
A Portable Liquid Chromatograph with a Battery-operated Compact Electroosmotic Pump and a Microfluidic Chip Device with a Reversed Phase Packed Column
| Title: | A Portable Liquid Chromatograph with a Battery-operated Compact Electroosmotic Pump and a Microfluidic Chip Device with a Reversed Phase Packed Column |
| Authors: | ISHIDA, Akihiko Browse this author | | FUJII, Mitsutaka Browse this author | | FUJIMOTO, Takehiro Browse this author | | SASAKI, Shunsuke Browse this author | | YANAGISAWA, Ichiro Browse this author | | TANI, Hirofumi Browse this author | | TOKESHI, Manabu Browse this author →KAKEN DB |
| Keywords: | electroosmotic pump | | liquid chromatography | | microfluidic chip | | packed column |
| Issue Date: | 10-Nov-2015 |
| Publisher: | 日本分析化学会 |
| Journal Title: | Analytical Sciences |
| Volume: | 31 |
| Issue: | 11 |
| Start Page: | 1163 |
| End Page: | 1169 |
| Publisher DOI: | 10.2116/analsci.31.1163 |
| PMID: | 26561261 |
| Abstract: | A compact and lightweight liquid chromatography system is presented with overall dimensions of 26 cm width × 18 cm length × 21 cm height and weight of 2 kg. This system comprises a battery-operated compact electroosmotic pump, a manual injector, a microfluidic chip device containing a packed column and an electrochemical detector, and a USB bus-powered potentiostat. The pumping system was designed for microfluidic-based reversed-phase liquid chromatography in which an electroosmotically generated water stream pushes the mobile phase via a diaphragm for the output. The flow rate ranged from 0 to 10 μL/min and had a high degree of precision. The pumping system operated continuously for over 24 h with dry batteries. The column formed in the microfluidic device was packed with 3-μm ODS particles with a length of 30 mm and a diameter of 0.8 mm. The results presented herein demonstrate the performance of the pumping system and the column using alkylphenols, catecholamine, catechin, and amino acids. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/71738 |
| Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 石田 晃彦
|
