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Hokkaido University Collection of Scholarly and Academic Papers >
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Peer-reviewed Journal Articles, etc >
Site-Selective and Stereoselective C(sp(3))-H Borylation of Alkyl Side Chains of 1,3-Azoles with a Silica-Supported Monophosphine-Iridium Catalyst
| Title: | Site-Selective and Stereoselective C(sp(3))-H Borylation of Alkyl Side Chains of 1,3-Azoles with a Silica-Supported Monophosphine-Iridium Catalyst |
| Authors: | Murakami, Ryo Browse this author | | Iwai, Tomohiro Browse this author | | Sawamura, Masaya Browse this author →KAKEN DB |
| Keywords: | 1,3-azole | | C-H activation | | borylation | | iridium | | heterogeneous catalyst |
| Issue Date: | May-2016 |
| Publisher: | Georg Thieme Verlag |
| Journal Title: | Synlett |
| Volume: | 27 |
| Issue: | 8 |
| Start Page: | 1187 |
| End Page: | 1192 |
| Publisher DOI: | 10.1055/s-0035-1561599 |
| Abstract: | Site-selective and stereoselective C(sp(3))-H borylation of alkyl side chains of 1,3-azoles with bis(pinacolato) diboron was effectively catalyzed by a silica-supported monophosphine-iridium catalyst. The borylation occurred under relatively mild conditions (2 mol% Ir, 5090 degrees C), affording the corresponding primary and secondary alkylboronates. This system was applicable to a variety of 1,3-(benzo) azoles such as thiazoles, oxazoles, and imidazoles. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/65194 |
| Appears in Collections: | 理学院・理学研究院 (Graduate School of Science / Faculty of Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 澤村 正也
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