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Detection of Autoreactive Type II NKT Cells: A Pilot Study of Comparison Between Healthy Individuals and Patients with Vasculitis.

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Title: Detection of Autoreactive Type II NKT Cells: A Pilot Study of Comparison Between Healthy Individuals and Patients with Vasculitis.
Authors: Nishioka, Yusuke Browse this author
Sonoda, Takaomi Browse this author
Shida, Haruki Browse this author
Kusunoki, Yoshihiro Browse this author
Hattanda, Fumihiko Browse this author
Tanimura, Shun Browse this author
Uozumi, Ryo Browse this author
Yamada, Mai Browse this author
Nishibata, Yuka Browse this author
Masuda, Sakiko Browse this author
Nakazawa, Daigo Browse this author
Tomaru, Utano Browse this author →KAKEN DB
Atsumi, Tatsuya Browse this author →KAKEN DB
Ishizu, Akihiro Browse this author →KAKEN DB
Keywords: CD1d tetramer
cytokine profile
sterol carrier protein 2
type II NKT cell
Issue Date: Nov-2018
Journal Title: Cytometry. Part A : the journal of the International Society for Analytical Cytology
Volume: 93
Issue: 11
Start Page: 1157
End Page: 1164
Publisher DOI: 10.1002/cyto.a.23618
PMID: 30253046
Abstract: NKT cells are defined as T cells that recognize hydrophobic antigens presented by class I MHC-like molecules, including CD1d. Among CD1d-restricted NKT cells, type I and type II subsets have been noted. CD1d-restricted type I NKT cells are regarded as pro-inflammatory cells in general. On the contrary, accumulated evidence has demonstrated an anti-inflammatory property of CD1d-restricted type II NKT cells. In our earlier study using a rat model with vasculitis, we demonstrated the pro-inflammatory function of CD1d-restricted type II NKT cells and identified that one such cell recognized P
Rights: This is the peer reviewed version of the following article: Cytometry Part A Volume 93, Issue 11, pages 1157–1164, Nov 2018, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Type: article (author version)
Appears in Collections:保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 石津 明洋

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