Title: | Detection of Autoreactive Type II NKT Cells: A Pilot Study of Comparison Between Healthy Individuals and Patients with Vasculitis. |
Authors: | Nishioka, Yusuke Browse this author |
Sonoda, Takaomi Browse this author |
Shida, Haruki Browse this author |
Kusunoki, Yoshihiro Browse this author |
Hattanda, Fumihiko Browse this author |
Tanimura, Shun Browse this author |
Uozumi, Ryo Browse this author |
Yamada, Mai Browse this author |
Nishibata, Yuka Browse this author |
Masuda, Sakiko Browse this author |
Nakazawa, Daigo Browse this author |
Tomaru, Utano Browse this author →KAKEN DB |
Atsumi, Tatsuya Browse this author →KAKEN DB |
Ishizu, Akihiro Browse this author →KAKEN DB |
Keywords: | CD1d tetramer |
cytokine profile |
sterol carrier protein 2 |
type II NKT cell |
vasculitis |
Issue Date: | Nov-2018 |
Journal Title: | Cytometry. Part A : the journal of the International Society for Analytical Cytology |
Volume: | 93 |
Issue: | 11 |
Start Page: | 1157 |
End Page: | 1164 |
Publisher DOI: | 10.1002/cyto.a.23618 |
PMID: | 30253046 |
Abstract: | NKT cells are defined as T cells that recognize hydrophobic antigens presented by class I MHC-like molecules, including CD1d. Among CD1d-restricted NKT cells, type I and type II subsets have been noted. CD1d-restricted type I NKT cells are regarded as pro-inflammatory cells in general. On the contrary, accumulated evidence has demonstrated an anti-inflammatory property of CD1d-restricted type II NKT cells. In our earlier study using a rat model with vasculitis, we demonstrated the pro-inflammatory function of CD1d-restricted type II NKT cells and identified that one such cell recognized P |
Rights: | This is the peer reviewed version of the following article: Cytometry Part A Volume 93, Issue 11, pages 1157–1164, Nov 2018, which has been published in final form at https://doi.org/10.1002/cyto.a.23618. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/76239 |
Appears in Collections: | 保健科学院・保健科学研究院 (Graduate School of Health Sciences / Faculty of Health Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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